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» Support vector machine for functional data classification
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JMLR
2010
147views more  JMLR 2010»
14 years 4 months ago
Image Denoising with Kernels Based on Natural Image Relations
A successful class of image denoising methods is based on Bayesian approaches working in wavelet representations. The performance of these methods improves when relations among th...
Valero Laparra, Juan Gutierrez, Gustavo Camps-Vall...
106
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BMCBI
2010
190views more  BMCBI 2010»
14 years 9 months ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...
BMCBI
2010
125views more  BMCBI 2010»
14 years 9 months ago
Large-scale prediction of protein-protein interactions from structures
Background: The prediction of protein-protein interactions is an important step toward the elucidation of protein functions and the understanding of the molecular mechanisms insid...
Martial Hue, Michael Riffle, Jean-Philippe Vert, W...
BMCBI
2007
130views more  BMCBI 2007»
14 years 9 months ago
Exploiting residue-level and profile-level interface propensities for usage in binding sites prediction of proteins
Background: Recognition of binding sites in proteins is a direct computational approach to the characterization of proteins in terms of biological and biochemical function. Residu...
Qiwen Dong, Xiaolong Wang, Lei Lin, Yi Guan
BMCBI
2006
120views more  BMCBI 2006»
14 years 9 months ago
Optimizing amino acid substitution matrices with a local alignment kernel
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
Hiroto Saigo, Jean-Philippe Vert, Tatsuya Akutsu