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NAR
2010
122views more  NAR 2010»
14 years 4 months ago
ELM: the status of the 2010 eukaryotic linear motif resource
Linear motifs are short segments of multidomain proteins that provide regulatory functions independently of protein tertiary structure. Much of intracellular signalling passes thr...
Cathryn M. Gould, Francesca Diella, Allegra Via, P...
NAR
1998
122views more  NAR 1998»
14 years 9 months ago
The PIR-International Protein Sequence Database
The Protein Information Resource (PIR; http://wwwnbrf.georgetown.edu/pir/ ) supports research on molecular evolution, functional genomics, and computational biology by maintaining...
Winona C. Barker, John S. Garavelli, Daniel H. Haf...
BMCBI
2006
85views more  BMCBI 2006»
14 years 9 months ago
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
Rui Jiang, Hua Yang, Fengzhu Sun, Ting Chen
87
Voted
GECCO
2007
Springer
211views Optimization» more  GECCO 2007»
15 years 3 months ago
An extremal optimization search method for the protein folding problem: the go-model example
The protein folding problem consists of predicting the functional (native) structure of the protein given its linear sequence of amino acids. Despite extensive progress made in un...
Alena Shmygelska
130
Voted
IWMM
2011
Springer
206views Hardware» more  IWMM 2011»
14 years 12 days ago
A comprehensive evaluation of object scanning techniques
At the heart of all garbage collectors lies the process of identifying and processing reference fields within an object. Despite its key role, and evidence of many different impl...
Robin Garner, Stephen M. Blackburn, Daniel Frampto...