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» Synthetic biology: from modules to systems
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BMCBI
2010
136views more  BMCBI 2010»
13 years 6 months ago
A hub-attachment based method to detect functional modules from confidence-scored protein interactions and expression profiles
Background: Many research results show that the biological systems are composed of functional modules. Members in the same module usually have common functions. This is useful inf...
Chia-Hao Chin, Shu-Hwa Chen, Chin-Wen Ho, Ming-Tat...
BMCBI
2007
80views more  BMCBI 2007»
13 years 6 months ago
Mining expression-dependent modules in the human interaction network
ent> <title> <p>Highlights from the Third International Society for Computational Biology (ISCB) Student Council Symposium at the Fifteenth Annual International Conf...
Elisabeth Georgii, Sabine Dietmann, Takeaki Uno, P...
CDC
2008
IEEE
14 years 21 days ago
Retroactivity attenuation in transcriptional networks: Design and analysis of an insulation device
— Retroactivity is a parasitic phenomenon that changes the desired input/output response of a system when it is connected to “downstream” systems. Downstream and upstream ref...
Domitilla Del Vecchio, Shridhar Jayanthi
RECOMB
2006
Springer
14 years 6 months ago
Genome-Wide Discovery of Modulators of Transcriptional Interactions in Human B Lymphocytes
Abstract. Transcriptional interactions in a cell are modulated by a variety of mechanisms that prevent their representation as pure pairwise interactions between a transcription fa...
Kai Wang, Ilya Nemenman, Nilanjana Banerjee, Adam ...
BMCBI
2010
202views more  BMCBI 2010»
13 years 6 months ago
NeMo: Network Module identification in Cytoscape
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
Corban G. Rivera, Rachit Vakil, Joel S. Bader