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» Synthetic biology - putting engineering into biology
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TCS
2011
14 years 6 months ago
An algorithmic framework for network reconstruction
Models of biological systems and phenomena are of high scientific interest and practical relevance, but not always easy to obtain due to their inherent complexity. To gain the re...
Markus Durzinsky, Annegret Wagler, Robert Weismant...
CISIS
2010
IEEE
15 years 6 months ago
Gene Ontology Rewritten for Computing Gene Functional Similarity
Abstract—Discovery biological organisation of the cell in modules network is a challenging task. Currently, approaches based on a controlled vocabulary, as Gene Ontology, to iden...
Alessia Visconti, Francesca Cordero, Marco Botta, ...
VMCAI
2004
Springer
15 years 5 months ago
A Grand Challenge for Computing: Towards Full Reactive Modeling of a Multi-cellular Animal
Biological systems can be modeled beneficially as reactive systems, using languages and tools developed for the construction of man-made systems. Our long-term aim is to model a f...
David Harel
PVLDB
2010
200views more  PVLDB 2010»
14 years 10 months ago
SAPPER: Subgraph Indexing and Approximate Matching in Large Graphs
With the emergence of new applications, e.g., computational biology, new software engineering techniques, social networks, etc., more data is in the form of graphs. Locating occur...
Shijie Zhang, Jiong Yang, Wei Jin
BMCBI
2005
169views more  BMCBI 2005»
14 years 11 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader