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» Synthetic biology - putting engineering into biology
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MAGS
2007
100views more  MAGS 2007»
14 years 11 months ago
Engineering agent-mediated integration of bioinformatics analysis tools
Abstract. The availability of massive amounts of biological data, distributed in various data sources, has prompted the development of a wide range of data analysis tools. However,...
Vassilis Koutkias, Andigoni Malousi, Nicos Maglave...
ALGORITHMICA
2008
115views more  ALGORITHMICA 2008»
14 years 12 months ago
Algorithm Engineering for Color-Coding with Applications to Signaling Pathway Detection
Color-coding is a technique to design fixed-parameter algorithms for several NP-complete subgraph isomorphism problems. Somewhat surprisingly, not much work has so far been spent ...
Falk Hüffner, Sebastian Wernicke, Thomas Zich...
IPPS
2006
IEEE
15 years 5 months ago
Parallel multiple sequence alignment with local phylogeny search by simulated annealing
The problem of multiple sequence alignment is one of the most important problems in computational biology. In this paper we present a new method that simultaneously performs multi...
Jaroslaw Zola, Denis Trystram, Andrei Tchernykh, C...
UAI
2008
15 years 1 months ago
Learning Hidden Markov Models for Regression using Path Aggregation
We consider the task of learning mappings from sequential data to real-valued responses. We present and evaluate an approach to learning a type of hidden Markov model (HMM) for re...
Keith Noto, Mark Craven
DNA
2008
Springer
15 years 1 months ago
A Simple DNA Gate Motif for Synthesizing Large-Scale Circuits
The prospects of programming molecular systems to perform complex autonomous tasks has motivated research into the design of synthetic biochemical circuits. Of particular interest ...
Lulu Qian, Erik Winfree