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» Synthetic biology - putting engineering into biology
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BMCBI
2006
113views more  BMCBI 2006»
14 years 12 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
BMCBI
2007
128views more  BMCBI 2007»
14 years 11 months ago
Model order selection for bio-molecular data clustering
Background: Cluster analysis has been widely applied for investigating structure in bio-molecular data. A drawback of most clustering algorithms is that they cannot automatically ...
Alberto Bertoni, Giorgio Valentini
NC
2008
122views Neural Networks» more  NC 2008»
14 years 11 months ago
Computation with finite stochastic chemical reaction networks
A highly desired part of the synthetic biology toolbox is an embedded chemical microcontroller, capable of autonomously following a logic program specified by a set of instructions...
David Soloveichik, Matthew Cook, Erik Winfree, Jeh...
TCBB
2008
107views more  TCBB 2008»
14 years 11 months ago
Coclustering of Human Cancer Microarrays Using Minimum Sum-Squared Residue Coclustering
It is a consensus in microarray analysis that identifying potential local patterns, characterized by coherent groups of genes and conditions, may shed light on the discovery of pre...
Hyuk Cho, Inderjit S. Dhillon
BMCBI
2005
128views more  BMCBI 2005»
14 years 11 months ago
Transformation and other factors of the peptide mass spectrometry pairwise peak-list comparison process
Background: Biological Mass Spectrometry is used to analyse peptides and proteins. A mass spectrum generates a list of measured mass to charge ratios and intensities of ionised pe...
Witold E. Wolski, Maciej Lalowski, Peter Martus, R...