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TCAD
2010
133views more  TCAD 2010»
14 years 6 months ago
Defect-Tolerant Design and Optimization of a Digital Microfluidic Biochip for Protein Crystallization
Protein crystallization is a commonly used technique for protein analysis and subsequent drug design. It predicts the 3-D arrangement of the constituent amino acids, which in turn ...
Tao Xu, Krishnendu Chakrabarty, Vamsee K. Pamula
TCAD
2010
118views more  TCAD 2010»
14 years 6 months ago
Design Tools for Digital Microfluidic Biochips: Toward Functional Diversification and More Than Moore
Abstract--Microfluidics-based biochips enable the precise control of nanoliter volumes of biochemical samples and reagents. They combine electronics with biology, and they integrat...
Krishnendu Chakrabarty, Richard B. Fair, Jun Zeng
TCBB
2010
96views more  TCBB 2010»
14 years 6 months ago
A Survey of Spatial Defects in Homo Sapiens Affymetrix GeneChips
Modern biology has moved from a science of individual measurements to a science where data are collected on an industrial scale. Foremost, among the new tools for biochemistry are ...
William B. Langdon, Graham J. G. Upton, Renata da ...
JGO
2011
89views more  JGO 2011»
14 years 2 months ago
Model building using bi-level optimization
Abstract In many problems from different disciplines such as engineering, physics, medicine, and biology, a series of experimental data is used in order to generate a model that ca...
Georges K. Saharidis, Ioannis P. Androulakis, Mari...
DAC
2011
ACM
13 years 11 months ago
Single-molecule electronic detection using nanoscale field-effect devices
Traditionally, biomolecular systems have been studied in ensemble. While much can be determined with ensemble measurements, scientific and technological interest is rapidly moving...
Sebastian Sorgenfrei, Kenneth L. Shepard