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BMCBI
2010
131views more  BMCBI 2010»
14 years 4 months ago
Dynamics based alignment of proteins: an alternative approach to quantify dynamic similarity
Background: The dynamic motions of many proteins are central to their function. It therefore follows that the dynamic requirements of a protein are evolutionary constrained. In or...
Márton Münz, Rune B. Lyngsø, Jo...
BMCBI
2010
104views more  BMCBI 2010»
14 years 4 months ago
A systematic study of genome context methods: calibration, normalization and combination
Background: Genome context methods have been introduced in the last decade as automatic methods to predict functional relatedness between genes in a target genome using the patter...
Luciana Ferrer, Joseph M. Dale, Peter D. Karp
BMCBI
2010
195views more  BMCBI 2010»
14 years 4 months ago
MBAT: A scalable informatics system for unifying digital atlasing workflows
Background: Digital atlases provide a common semantic and spatial coordinate system that can be leveraged to compare, contrast, and correlate data from disparate sources. As the q...
Daren Lee, Seth Ruffins, Queenie Ng, Nikhil Sane, ...
AUTOMATICA
2011
14 years 4 months ago
Sequential linear quadratic control of bilinear parabolic PDEs based on POD model reduction
We present a framework to solve a finite-time optimal control problem for parabolic partial differential equations (PDEs) with diffusivity-interior actuators, which is motivate...
Chao Xu, Yongsheng Ou, Eugenio Schuster
BMCBI
2011
14 years 4 months ago
A novel approach to the clustering of microarray data via nonparametric density estimation
Background: Cluster analysis is a crucial tool in several biological and medical studies dealing with microarray data. Such studies pose challenging statistical problems due to di...
Riccardo De Bin, Davide Risso
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