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» TRANSFAC: an integrated system for gene expression regulatio...
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CCE
2005
14 years 9 months ago
Numerical simulation of stochastic gene circuits
Armed with increasingly fast supercomputers and greater knowledge of the molecular mechanisms of gene expression, it is now practical to numerically simulate complex networks of r...
Howard Salis, Yiannis N. Kaznessis
BMCBI
2007
113views more  BMCBI 2007»
14 years 10 months ago
CoryneRegNet 4.0 - A reference database for corynebacterial gene regulatory networks
Background: Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of micr...
Jan Baumbach
DILS
2005
Springer
15 years 3 months ago
Hybrid Integration of Molecular-Biological Annotation Data
: We present a new approach to integrate annotation data from public sources for the expression analysis of genes and proteins. Expression data is materialized in a data warehouse ...
Toralf Kirsten, Hong Hai Do, Christine Körner...
BMCBI
2010
118views more  BMCBI 2010»
14 years 10 months ago
Identifying differentially regulated subnetworks from phosphoproteomic data
Background: Various high throughput methods are available for detecting regulations at the level of transcription, translation or posttranslation (e.g. phosphorylation). Integrati...
Martin Klammer, Klaus Godl, Andreas Tebbe, Christo...
BMCBI
2007
126views more  BMCBI 2007»
14 years 10 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...