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» TRANSFAC: an integrated system for gene expression regulatio...
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CIBCB
2005
IEEE
14 years 12 months ago
A Transcriptional Approach to Gene Clustering
— We present an integrative method for clustering coregulated genes and elucidating their underlying regulatory mechanisms. We use multi-state partition functions and thermodynam...
Ilias Tagkopoulos
CSB
2005
IEEE
161views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Data Integration in the Mouse Genome Informatics (MGI) Database
The Mouse Genome Informatics (MGI) Database at The Jackson Laboratory provides a comprehensive public resource about the laboratory mouse. MGI curated data types include gene repr...
Donnie Qi, Judith A. Blake, James A. Kadin, Joel E...
BMCBI
2007
139views more  BMCBI 2007»
14 years 10 months ago
Bioinformatics analysis of the early inflammatory response in a rat thermal injury model
Background: Thermal injury is among the most severe forms of trauma and its effects are both local and systemic. Response to thermal injury includes cellular protection mechanisms...
Eric Yang, Timothy Maguire, Martin L. Yarmush, Fra...
GLVLSI
2003
IEEE
175views VLSI» more  GLVLSI 2003»
15 years 3 months ago
A custom FPGA for the simulation of gene regulatory networks
We present a unique FPGA that uses a mix of digital and large-signal analog computation for the simulation of gene regulatory networks. The prototype IC consists of a 4x5 array of...
Ilias Tagkopoulos, Charles A. Zukowski, German Cav...
BMCBI
2010
118views more  BMCBI 2010»
14 years 10 months ago
Testing for mean and correlation changes in microarray experiments: an application for pathway analysis
Background: Microarray experiments examine the change in transcript levels of tens of thousands of genes simultaneously. To derive meaningful data, biologists investigate the resp...
Mayer Alvo, Zhongzhu Liu, Andrew Williams, Carole ...