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» TRANSFAC: an integrated system for gene expression regulatio...
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BMCBI
2008
129views more  BMCBI 2008»
14 years 10 months ago
Motif-directed network component analysis for regulatory network inference
Background: Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data a...
Chen Wang, Jianhua Xuan, Li Chen, Po Zhao, Yue Wan...
RECOMB
2007
Springer
15 years 4 months ago
Network Legos: Building Blocks of Cellular Wiring Diagrams
Publicly-available data sets provide detailed and large-scale information on multiple types of molecular interaction networks in a number of model organisms. These multi-modal univ...
T. M. Murali, Corban G. Rivera
JIB
2010
107views more  JIB 2010»
14 years 4 months ago
Integration of -omics data and networks for biomedical research with VANTED
Increasingly, research focus in the fields of biology and medicine moves from the investigation of single phenomena to the analysis of complex cause and effect relationships. The ...
Christian Klukas, Falk Schreiber
BMCBI
2006
156views more  BMCBI 2006»
14 years 10 months ago
Bayesian models for pooling microarray studies with multiple sources of replications
Background: Biologists often conduct multiple but different cDNA microarray studies that all target the same biological system or pathway. Within each study, replicate slides with...
Erin M. Conlon, Joon J. Song, Jun S. Liu
BMCBI
2006
139views more  BMCBI 2006»
14 years 10 months ago
Integrated functional visualization of eukaryotic genomes
Background: Increasing amounts of data from large scale whole genome analysis efforts demands convenient tools for manipulation, visualization and investigation. Whole genome plot...
Rohit Ghai, Hannes Lindemann, Trinad Chakraborty