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BMCBI
2004
140views more  BMCBI 2004»
14 years 9 months ago
What can we learn from noncoding regions of similarity between genomes?
Background: In addition to known protein-coding genes, large amounts of apparently non-coding sequence are conserved between the human and mouse genomes. It seems reasonable to as...
Thomas A. Down, Tim J. P. Hubbard
BMCBI
2005
115views more  BMCBI 2005»
14 years 9 months ago
MPrime: efficient large scale multiple primer and oligonucleotide design for customized gene microarrays
Background: Enhancements in sequencing technology have recently yielded assemblies of large genomes including rat, mouse, human, fruit fly, and zebrafish. The availability of larg...
Eric C. Rouchka, Abdelnaby Khalyfa, Nigel G. F. Co...
BIOINFORMATICS
2007
123views more  BIOINFORMATICS 2007»
14 years 10 months ago
A comparative genome approach to marker ordering
Motivation: Genome maps are fundamental to the study of an organism and essential in the process of genome sequencing which in turn provides the ultimate map of the genome. The in...
Thomas Faraut, Simon de Givry, Patrick Chabrier, T...
BMCBI
2004
115views more  BMCBI 2004»
14 years 9 months ago
An SVD-based comparison of nine whole eukaryotic genomes supports a coelomate rather than ecdysozoan lineage
Background: Eukaryotic whole genome sequences are accumulating at an impressive rate. Effective methods for comparing multiple whole eukaryotic genomes on a large scale are needed...
Gary W. Stuart, Michael W. Berry
BMCBI
2005
180views more  BMCBI 2005»
14 years 9 months ago
arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays
Background: The availability of the human genome sequence as well as the large number of physically accessible oligonucleotides, cDNA, and BAC clones across the entire genome has ...
Björn Menten, Filip Pattyn, Katleen De Preter...