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CSB
2004
IEEE
15 years 1 months ago
Navigating through the Biological Maze
Advances in genome science have created a surge of data. These data critical to scientific discovery are made available in thousands of heterogeneous public resources. Each of the...
Zoé Lacroix, Kaushal Parekh, Louiqa Raschid...
CSB
2004
IEEE
126views Bioinformatics» more  CSB 2004»
15 years 1 months ago
Boosted PRIM with Application to Searching for Oncogenic Pathway of Lung Cancer
Boosted PRIM (Patient Rule Induction Method) is a new algorithm developed for two-class classification problems. PRIM is a variation of those Tree-Based methods ( [4] Ch9.3), seek...
Pei Wang, Young Kim, Jonathan R. Pollack, Robert T...
GCB
2004
Springer
223views Biometrics» more  GCB 2004»
15 years 1 months ago
PoSSuMsearch: Fast and Sensitive Matching of Position Specific Scoring Matrices using Enhanced Suffix Arrays
: In biological sequence analysis, position specific scoring matrices (PSSMs) are widely used to represent sequence motifs. In this paper, we present a new nonheuristic algorithm, ...
Michael Beckstette, Dirk Strothmann, Robert Homann...
APBC
2004
163views Bioinformatics» more  APBC 2004»
14 years 11 months ago
A Combined Model and a Varied Gibbs Sampling Algorithm Used for Motif Discovery
The conserved sequences in gene regulatory regions dominate gene regulation. Discovering these sequences and their functions is important in post genome era. A novel model is cons...
Xiaoming Wu, Bo Wang, Changxin Song, Jingzhi Cheng
ALIFE
2004
14 years 9 months ago
Development and the Baldwin Effect
Baldwin's classic hypothesis states that behavioral plasticity can speed evolution by (a) smoothing the fitness landscape and (b) indirect genetic assimilation of acquired cha...
Keith L. Downing