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SDM
2004
SIAM
187views Data Mining» more  SDM 2004»
14 years 11 months ago
Minimum Sum-Squared Residue Co-Clustering of Gene Expression Data
Microarray experiments have been extensively used for simultaneously measuring DNA expression levels of thousands of genes in genome research. A key step in the analysis of gene e...
Hyuk Cho, Inderjit S. Dhillon, Yuqiang Guan, Suvri...
BIODATAMINING
2008
130views more  BIODATAMINING 2008»
14 years 9 months ago
Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profil
Background: Contrary to the traditional biology approach, where the expression patterns of a handful of genes are studied at a time, microarray experiments enable biologists to st...
Qicheng Ma, Gung-Wei Chirn, Joseph D. Szustakowski...
BMCBI
2010
113views more  BMCBI 2010»
14 years 9 months ago
Statistical method on nonrandom clustering with application to somatic mutations in cancer
Background: Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a conse...
Jingjing Ye, Adam Pavlícek, Elizabeth A. Lu...
BMCBI
2005
135views more  BMCBI 2005»
14 years 9 months ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...
BMCBI
2004
150views more  BMCBI 2004»
14 years 9 months ago
Graph-based iterative Group Analysis enhances microarray interpretation
Background: One of the most time-consuming tasks after performing a gene expression experiment is the biological interpretation of the results by identifying physiologically impor...
Rainer Breitling, Anna Amtmann, Pawel Herzyk