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BMCBI
2011
14 years 9 months ago
GCOD - GeneChip Oncology Database
Background: DNA microarrays have become a nearly ubiquitous tool for the study of human disease, and nowhere is this more true than in cancer. With hundreds of studies and thousan...
Fenglong Liu, Joseph White, Corina Antonescu, John...
BMCBI
2011
14 years 9 months ago
Dr. PIAS: an integrative system for assessing the druggability of protein-protein interactions
Background: The amount of data on protein-protein interactions (PPIs) available in public databases and in the literature has rapidly expanded in recent years. PPI data can provid...
Nobuyoshi Sugaya, Toshio Furuya
BMCBI
2011
14 years 9 months ago
Removing Noise From Pyrosequenced Amplicons
Background: In many environmental genomics applications a homologous region of DNA from a diverse sample is first amplified by PCR and then sequenced. The next generation sequenci...
Christopher Quince, Anders Lanzén, Russell ...
BMCBI
2011
14 years 9 months ago
pROC: an open-source package for R and S+ to analyze and compare ROC curves
Background: Receiver operating characteristic (ROC) curves are useful tools to evaluate classifiers in biomedical and bioinformatics applications. However, conclusions are often r...
Xavier Robin, Natacha Turck, Alexandre Hainard, Na...
BMCBI
2011
14 years 9 months ago
Statistical Test of Expression Pattern (STEPath): a new strategy to integrate gene expression data with genomic information in i
Background: In the last decades, microarray technology has spread, leading to a dramatic increase of publicly available datasets. The first statistical tools developed were focuse...
Paolo G. V. Martini, Davide Risso, Gabriele Sales,...
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