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BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
15 years 3 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
153
Voted
BMCBI
2006
149views more  BMCBI 2006»
15 years 3 months ago
Curation of viral genomes: challenges, applications and the way forward
Background: Whole genome sequence data is a step towards generating the 'parts list' of life to understand the underlying principles of Biocomplexity. Genome sequencing ...
Urmila Kulkarni-Kale, Shriram Bhosle, G. Sunitha M...
BMCBI
2006
135views more  BMCBI 2006»
15 years 3 months ago
iHAP - integrated haplotype analysis pipeline for characterizing the haplotype structure of genes
Background: The advent of genotype data from large-scale efforts that catalog the genetic variants of different populations have given rise to new avenues for multifactorial disea...
Chun Meng Song, Boon Huat Yeo, Erwin Tantoso, Yuch...
142
Voted
BMCBI
2007
168views more  BMCBI 2007»
15 years 3 months ago
Bayesian model-based inference of transcription factor activity
Background: In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is co...
Simon Rogers, Raya Khanin, Mark Girolami
JAIR
1998
89views more  JAIR 1998»
15 years 3 months ago
An Empirical Approach to Temporal Reference Resolution
Scheduling dialogs, during which people negotiate the times of appointments, are common in everyday life. This paper reports the results of an in-depth empirical investigation of ...
Janyce Wiebe, Thomas P. O'Hara, Thorsten Öhrs...