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131
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BMCBI
2010
156views more  BMCBI 2010»
15 years 2 months ago
Global screening of potential Candida albicans biofilm-related transcription factors via network comparison
Background: Candida albicans is a commonly encountered fungal pathogen in humans. The formation of biofilm is a major virulence factor in C. albicans pathogenesis and is related t...
Yu-Chao Wang, Chung-Yu Lan, Wen-Ping Hsieh, Luis A...
112
Voted
BMCBI
2010
102views more  BMCBI 2010»
15 years 2 months ago
Alignment and clustering of phylogenetic markers - implications for microbial diversity studies
Background: Molecular studies of microbial diversity have provided many insights into the bacterial communities inhabiting the human body and the environment. A common first step ...
James Robert White, Saket Navlakha, Niranjan Nagar...
BMCBI
2010
103views more  BMCBI 2010»
15 years 2 months ago
Nonparametric methods for the analysis of single-color pathogen microarrays
Background: The analysis of oligonucleotide microarray data in pathogen surveillance and discovery is a challenging task. Target template concentration, nucleic acid integrity, an...
Omar J. Jabado, Sean Conlan, P. Lan Quan, Jeffrey ...
121
Voted
BMCBI
2010
208views more  BMCBI 2010»
15 years 2 months ago
Using machine learning to speed up manual image annotation: application to a 3D imaging protocol for measuring single cell gene
Background: Image analysis is an essential component in many biological experiments that study gene expression, cell cycle progression, and protein localization. A protocol for tr...
Zafer Aydin, John I. Murray, Robert H. Waterston, ...
BMCBI
2010
105views more  BMCBI 2010»
15 years 2 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang