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» Technologies for Integrating Biological Data
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BMCBI
2010
115views more  BMCBI 2010»
14 years 12 months ago
Integration of multiple data sources to prioritize candidate genes using discounted rating system
Background: Identifying disease gene from a list of candidate genes is an important task in bioinformatics. The main strategy is to prioritize candidate genes based on their simil...
Yongjin Li, Jagdish Chandra Patra
BMCBI
2006
94views more  BMCBI 2006»
14 years 12 months ago
Simulation of microarray data with realistic characteristics
Background: Microarray technologies have become common tools in biological research. As a result, a need for effective computational methods for data analysis has emerged. Numerou...
Matti Nykter, Tommi Aho, Miika Ahdesmäki, Pek...
BMCBI
2007
123views more  BMCBI 2007»
14 years 12 months ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
CBMS
2004
IEEE
15 years 3 months ago
Toward a Systems Biology Software Toolkit
Insight to complex problems may be revealed when domain data sets are viewed or structured in new and innovative ways. Systems approaches to biomedical problems fundamentally invo...
Donald J. Johann, Michael D. McGuigan, Stanimire T...
PREMI
2005
Springer
15 years 5 months ago
Computational Molecular Biology of Genome Expression and Regulation
Abstract. Technological advances in experimental and computational molecular biology have revolutionized the whole fields of biology and medicine. Large-scale sequencing, expressio...
Michael Q. Zhang