Background: Identifying disease gene from a list of candidate genes is an important task in bioinformatics. The main strategy is to prioritize candidate genes based on their simil...
Background: Microarray technologies have become common tools in biological research. As a result, a need for effective computational methods for data analysis has emerged. Numerou...
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
Insight to complex problems may be revealed when domain data sets are viewed or structured in new and innovative ways. Systems approaches to biomedical problems fundamentally invo...
Donald J. Johann, Michael D. McGuigan, Stanimire T...
Abstract. Technological advances in experimental and computational molecular biology have revolutionized the whole fields of biology and medicine. Large-scale sequencing, expressio...