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CSB
2004
IEEE
135views Bioinformatics» more  CSB 2004»
15 years 1 months ago
Selection of Patient Samples and Genes for Outcome Prediction
Gene expression profiles with clinical outcome data enable monitoring of disease progression and prediction of patient survival at the molecular level. We present a new computatio...
Huiqing Liu, Jinyan Li, Limsoon Wong
BMCBI
2010
132views more  BMCBI 2010»
14 years 9 months ago
Protein docking by Rotation-Based Uniform Sampling (RotBUS) with fast computing of intermolecular contact distance and residue d
Background: Protein-protein interactions are fundamental for the majority of cellular processes and their study is of enormous biotechnological and therapeutic interest. In recent...
Albert Solernou, Juan Fernández-Recio
BMCBI
2010
150views more  BMCBI 2010»
14 years 9 months ago
Evolutionary rates at codon sites may be used to align sequences and infer protein domain function
Background: Sequence alignments form part of many investigations in molecular biology, including the determination of phylogenetic relationships, the prediction of protein structu...
Pierre M. Durand, Scott Hazelhurst, Theresa L. Coe...
APBC
2004
132views Bioinformatics» more  APBC 2004»
14 years 11 months ago
A Novel Feature Selection Method to Improve Classification of Gene Expression Data
This paper introduces a novel method for minimum number of gene (feature) selection for a classification problem based on gene expression data with an objective function to maximi...
Liang Goh, Qun Song, Nikola K. Kasabov
JCB
2006
123views more  JCB 2006»
14 years 9 months ago
Reconstructing Ancestral Haplotypes with a Dictionary Model
We propose a dictionary model for haplotypes. According to the model, a haplotype is constructed by randomly concatenating haplotype segments from a given dictionary of segments. ...
Kristin L. Ayers, Chiara Sabatti, Kenneth Lange