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» Testing Polymorphic Properties
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BMCBI
2007
127views more  BMCBI 2007»
14 years 11 months ago
Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines
Background: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The no...
Jian Tian, Ningfeng Wu, Xuexia Guo, Jun Guo, Juhua...
BMCBI
2006
138views more  BMCBI 2006»
14 years 11 months ago
Approximation properties of haplotype tagging
Background: Single nucleotide polymorphisms (SNPs) are locations at which the genomic sequences of population members differ. Since these differences are known to follow patterns,...
Staal A. Vinterbo, Stephan Dreiseitl, Lucila Ohno-...
ICFP
1999
ACM
15 years 4 months ago
A Simple Proof Technique for Certain Parametricity Results
Many properties of parametric, polymorphic functions can be determined simply by inspection of their types. Such results are usually proven using Reynolds's parametricity the...
Karl Crary
100
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POPL
1995
ACM
15 years 3 months ago
Compiling Polymorphism Using Intensional Type Analysis
Traditional techniques for implementing polymorphism use a universal representation for objects of unknown type. Often, this forces a compiler to use universal representations eve...
Robert Harper, J. Gregory Morrisett
BMCBI
2006
132views more  BMCBI 2006»
14 years 11 months ago
Genome-wide DNA polymorphism analyses using VariScan
Background: DNA sequence polymorphisms analysis can provide valuable information on the evolutionary forces shaping nucleotide variation, and provides an insight into the function...
Stephan Hutter, Albert J. Vilella, Julio Rozas