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BMCBI
2007
135views more  BMCBI 2007»
15 years 4 months ago
Sequence similarity is more relevant than species specificity in probabilistic backtranslation
Background: Backtranslation is the process of decoding a sequence of amino acids into the corresponding codons. All synthetic gene design systems include a backtranslation module....
Alfredo Ferro, Rosalba Giugno, Giuseppe Pigola, Al...
BMCBI
2007
122views more  BMCBI 2007»
15 years 4 months ago
TAP score: torsion angle propensity normalization applied to local protein structure evaluation
Background: Experimentally determined protein structures may contain errors and require validation. Conformational criteria based on the Ramachandran plot are mainly used to disti...
Silvio C. E. Tosatto, Roberto Battistutta
BMCBI
2006
137views more  BMCBI 2006»
15 years 4 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
CONNECTION
2006
172views more  CONNECTION 2006»
15 years 4 months ago
Temporal sequence detection with spiking neurons: towards recognizing robot language instructions
We present an approach for recognition and clustering of spatio temporal patterns based on networks of spiking neurons with active dendrites and dynamic synapses. We introduce a n...
Christo Panchev, Stefan Wermter
BMCBI
2007
164views more  BMCBI 2007»
15 years 4 months ago
Comparison of probabilistic Boolean network and dynamic Bayesian network approaches for inferring gene regulatory networks
Background: The regulation of gene expression is achieved through gene regulatory networks (GRNs) in which collections of genes interact with one another and other substances in a...
Peng Li, Chaoyang Zhang, Edward J. Perkins, Ping G...
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