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140
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BMCBI
2010
135views more  BMCBI 2010»
15 years 3 months ago
Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization
Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...
Marc Hulsman, Anouk Mentink, Eugene P. van Someren...
128
Voted
BMCBI
2010
129views more  BMCBI 2010»
15 years 3 months ago
LAITOR - Literature Assistant for Identification of Terms co-Occurrences and Relationships
Background: Biological knowledge is represented in scientific literature that often describes the function of genes/ proteins (bioentities) in terms of their interactions (biointe...
Adriano Barbosa-Silva, Theodoros G. Soldatos, Ivan...
155
Voted
BMCBI
2010
189views more  BMCBI 2010»
15 years 3 months ago
High quality protein sequence alignment by combining structural profile prediction and profile alignment using SABERTOOTH
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
Florian Teichert, Jonas Minning, Ugo Bastolla, Mar...
128
Voted
BMCBI
2007
168views more  BMCBI 2007»
15 years 3 months ago
Benchmarking consensus model quality assessment for protein fold recognition
Background: Selecting the highest quality 3D model of a protein structure from a number of alternatives remains an important challenge in the field of structural bioinformatics. M...
Liam J. McGuffin
147
Voted
BMCBI
2010
151views more  BMCBI 2010»
15 years 3 months ago
TF-finder: A software package for identifying transcription factors involved in biological processes using microarray data and e
Background: Identification of transcription factors (TFs) involved in a biological process is the first step towards a better understanding of the underlying regulatory mechanisms...
Xiaoqi Cui, Tong Wang, Huann-Sheng Chen, Victor Bu...