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BMCBI
2010
186views more  BMCBI 2010»
14 years 9 months ago
Knowledge-based biomedical word sense disambiguation: comparison of approaches
Background: Word sense disambiguation (WSD) algorithms attempt to select the proper sense of ambiguous terms in text. Resources like the UMLS provide a reference thesaurus to be u...
Antonio Jimeno Yepes, Alan R. Aronson
BMCBI
2008
145views more  BMCBI 2008»
14 years 9 months ago
Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis
Background: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, ...
Shameek Biswas, John D. Storey, Joshua M. Akey
BMCBI
2008
166views more  BMCBI 2008»
14 years 9 months ago
Biclustering via optimal re-ordering of data matrices in systems biology: rigorous methods and comparative studies
Background: The analysis of large-scale data sets via clustering techniques is utilized in a number of applications. Biclustering in particular has emerged as an important problem...
Peter A. DiMaggio Jr., Scott R. McAllister, Christ...
BMCBI
2008
102views more  BMCBI 2008»
14 years 9 months ago
Improving protein function prediction methods with integrated literature data
Background: Determining the function of uncharacterized proteins is a major challenge in the post-genomic era due to the problem's complexity and scale. Identifying a protein...
Aaron Gabow, Sonia M. Leach, William A. Baumgartne...
BMCBI
2008
143views more  BMCBI 2008»
14 years 9 months ago
catmap: Case-control And TDT Meta-Analysis Package
Background: Risk for complex disease is thought to be controlled by multiple genetic risk factors, each with small individual effects. Meta-analyses of several independent studies...
Kristin K. Nicodemus