This paper addresses challenges to resource managers' use of scientific research, and reports strategies and informatics tools to ameliorate those challenges. Our work involv...
Natalie Kopytko, Judith Bayard Cushing, Lee Zeman,...
Abduction is a fundamental form of nonmonotonic reasoning that aims at finding explanations for observed manifestations. This process underlies many applications, from car configu...
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Background: Knowing the subcellular location of proteins provides clues to their function as well as the interconnectivity of biological processes. Dozens of tools are available f...
Background: Large-scale sequencing of entire genomes has ushered in a new age in biology. One of the next grand challenges is to dissect the cellular networks consisting of many i...