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BMCBI
2006
172views more  BMCBI 2006»
14 years 9 months ago
A novel scoring schema for peptide identification by searching protein sequence databases using tandem mass spectrometry data
Background: Tandem mass spectrometry (MS/MS) is a powerful tool for protein identification. Although great efforts have been made in scoring the correlation between tandem mass sp...
Zhuo Zhang, Shiwei Sun, Xiaopeng Zhu, Suhua Chang,...
BMCBI
2006
142views more  BMCBI 2006»
14 years 9 months ago
Improving the Performance of SVM-RFE to Select Genes in Microarray Data
Background: Recursive Feature Elimination is a common and well-studied method for reducing the number of attributes used for further analysis or development of prediction models. ...
Yuanyuan Ding, Dawn Wilkins
BMCBI
2006
154views more  BMCBI 2006»
14 years 9 months ago
Automated recognition of malignancy mentions in biomedical literature
Background: The rapid proliferation of biomedical text makes it increasingly difficult for researchers to identify, synthesize, and utilize developed knowledge in their fields of ...
Yang Jin, Ryan T. McDonald, Kevin Lerman, Mark A. ...
BMCBI
2006
139views more  BMCBI 2006»
14 years 9 months ago
Improvement in accuracy of multiple sequence alignment using novel group-to-group sequence alignment algorithm with piecewise li
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...
Shinsuke Yamada, Osamu Gotoh, Hayato Yamana
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BMCBI
2006
127views more  BMCBI 2006»
14 years 9 months ago
PathogenMIPer: a tool for the design of molecular inversion probes to detect multiple pathogens
Background: Here we describe PathogenMIPer, a software program for designing molecular inversion probe (MIP) oligonucleotides for use in pathogen identification and detection. The...
Sreedevi Thiyagarajan, Miloslav Karhanek, Michael ...
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