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BMCBI
2007
106views more  BMCBI 2007»
14 years 9 months ago
Improved classification accuracy in 1- and 2-dimensional NMR metabolomics data using the variance stabilising generalised logari
Background: Classifying nuclear magnetic resonance (NMR) spectra is a crucial step in many metabolomics experiments. Since several multivariate classification techniques depend up...
Helen M. Parsons, Christian Ludwig, Ulrich L. G&uu...
BMCBI
2007
144views more  BMCBI 2007»
14 years 9 months ago
Application of amino acid occurrence for discriminating different folding types of globular proteins
Background: Predicting the three-dimensional structure of a protein from its amino acid sequence is a long-standing goal in computational/molecular biology. The discrimination of ...
Y.-h. Taguchi, M. Michael Gromiha
BMCBI
2008
121views more  BMCBI 2008»
14 years 9 months ago
Stability of gene contributions and identification of outliers in multivariate analysis of microarray data
Background: Multivariate ordination methods are powerful tools for the exploration of complex data structures present in microarray data. These methods have several advantages com...
Florent Baty, Daniel Jaeger, Frank Preiswerk, Mart...
BMCBI
2008
110views more  BMCBI 2008»
14 years 9 months ago
Enhancing the prediction of protein pairings between interacting families using orthology information
Background: It has repeatedly been shown that interacting protein families tend to have similar phylogenetic trees. These similarities can be used to predicting the mapping betwee...
José M. G. Izarzugaza, David de Juan, Carle...
BMCBI
2008
185views more  BMCBI 2008»
14 years 9 months ago
Mining clinical relationships from patient narratives
Background: The Clinical E-Science Framework (CLEF) project has built a system to extract clinically significant information from the textual component of medical records in order...
Angus Roberts, Robert J. Gaizauskas, Mark Hepple, ...