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BMCBI
2005
80views more  BMCBI 2005»
14 years 9 months ago
Gene finding in the chicken genome
Background: Despite the continuous production of genome sequence for a number of organisms, reliable, comprehensive, and cost effective gene prediction remains problematic. This i...
Eduardo Eyras, Alexandre Reymond, Robert Castelo, ...
BMCBI
2005
103views more  BMCBI 2005»
14 years 9 months ago
Many accurate small-discriminatory feature subsets exist in microarray transcript data: biomarker discovery
Background: Molecular profiling generates abundance measurements for thousands of gene transcripts in biological samples such as normal and tumor tissues (data points). Given such...
Leslie Grate
BMCBI
2005
306views more  BMCBI 2005»
14 years 9 months ago
A method for aligning RNA secondary structures and its application to RNA motif detection
Background: Alignment of RNA secondary structures is important in studying functional RNA motifs. In recent years, much progress has been made in RNA motif finding and structure a...
Jianghui Liu, Jason Tsong-Li Wang, Jun Hu, Bin Tia...
BMCBI
2005
107views more  BMCBI 2005»
14 years 9 months ago
ProbeMaker: an extensible framework for design of sets of oligonucleotide probes
Background: Procedures for genetic analyses based on oligonucleotide probes are powerful tools that can allow highly parallel investigations of genetic material. Such procedures r...
Johan Stenberg, Mats Nilsson, Ulf Landegren
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BMCBI
2005
152views more  BMCBI 2005»
14 years 9 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer