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105
Voted
BMCBI
2008
14 years 10 months ago
2008
Background: Ontologies such as the Gene Ontology can enable the construction of complex queries over biological information in a conceptual way, however existing systems to do thi...
96
Voted
BMCBI
2007
14 years 10 months ago
2007
Background: Innovative extensions of (M) ANOVA gain common ground for the analysis of designed metabolomics experiments. ASCA is such a multivariate analysis method; it has succes...
BMCBI
2010
14 years 10 months ago
2010
Background: The occurrence of a genetic bottleneck in HIV sexual or mother-to-infant transmission has been well documented. This results in a majority of new infections being homo...
107
Voted
BMCBI
2008
14 years 10 months ago
2008
Background: Microarray experiments measure changes in the expression of thousands of genes. The resulting lists of genes with changes in expression are then searched for biologica...
BMCBI
2008
14 years 10 months ago
2008
Background: In real-time quantitative PCR studies using absolute plasmid DNA standards, a calibration curve is developed to estimate an unknown DNA concentration. However, potenti...