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BMCBI
2007
131views more  BMCBI 2007»
14 years 9 months ago
FUNC: a package for detecting significant associations between gene sets and ontological annotations
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...
Kay Prüfer, Bjoern Muetzel, Hong Hai Do, Gunt...
BMCBI
2010
172views more  BMCBI 2010»
14 years 9 months ago
Inferring gene regression networks with model trees
Background: Novel strategies are required in order to handle the huge amount of data produced by microarray technologies. To infer gene regulatory networks, the first step is to f...
Isabel A. Nepomuceno-Chamorro, Jesús S. Agu...
BMCBI
2008
97views more  BMCBI 2008»
14 years 9 months ago
Large-scale directional relationship extraction and resolution
Background: Relationships between entities such as genes, chemicals, metabolites, phenotypes and diseases in MEDLINE are often directional. That is, one may affect the other in a ...
Cory B. Giles, Jonathan D. Wren
BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
14 years 9 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
ECCC
2006
134views more  ECCC 2006»
14 years 9 months ago
Derandomizing the AW matrix-valued Chernoff bound using pessimistic estimators and applications
Ahlswede and Winter [AW02] introduced a Chernoff bound for matrix-valued random variables, which is a non-trivial generalization of the usual Chernoff bound for real-valued random...
Avi Wigderson, David Xiao