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124
Voted
BMCBI
2007
15 years 6 months ago
2007
Background: Orthology is one of the cornerstones of gene function prediction. Dividing the phylogenetic relations between genes into either orthologs or paralogs is however an ove...
192
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BMCBI
2008
15 years 6 months ago
2008
Background: DNA microarray technology allows for the measurement of genome-wide expression patterns. Within the resultant mass of data lies the problem of analyzing and presenting...
151
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BMCBI
2008
15 years 6 months ago
2008
Background: In DNA microarray experiments, discovering groups of genes that share similar transcriptional characteristics is instrumental in functional annotation, tissue classifi...
148
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BMCBI
2008
15 years 6 months ago
2008
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
171
Voted
BMCBI
2008
15 years 6 months ago
2008
Background: Protein domains present some of the most useful information that can be used to understand protein structure and functions. Recent research on protein domain boundary ...