Background: Since proteins perform their functions by interacting with one another and with other biomolecules, reconstructing a map of the protein-protein interactions of a cell,...
Xiaomei Wu, Lei Zhu, Jie Guo, Cong Fu, Hongjun Zho...
Background: Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an "echo" of real molecular processes in the cell...
Alexander E. Kel, Nico Voss, Ruy Jauregui, Olga V....
Background: Designing novel proteins with site-directed recombination has enormous prospects. By locating effective recombination sites for swapping sequence parts, the probabilit...
Background: Tiling microarrays are becoming an essential technology in the functional genomics toolbox. They have been applied to the tasks of novel transcript identification, elu...
Thomas E. Royce, Nicholas Carriero, Mark B. Gerste...
Background: Many important high throughput projects use in situ hybridization and may require the analysis of images of spatial cross sections of organisms taken with cellular lev...
Manjunatha Jagalur, Chris Pal, Erik G. Learned-Mil...