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BMCBI
2008
114views more  BMCBI 2008»
14 years 10 months ago
Dinucleotide controlled null models for comparative RNA gene prediction
Background: Comparative prediction of RNA structures can be used to identify functional noncoding RNAs in genomic screens. It was shown recently by Babak et al. [BMC Bioinformatic...
Tanja Gesell, Stefan Washietl
BMCBI
2008
143views more  BMCBI 2008»
14 years 10 months ago
Automatic detection of exonic splicing enhancers (ESEs) using SVMs
Background: Exonic splicing enhancers (ESEs) activate nearby splice sites and promote the inclusion (vs. exclusion) of exons in which they reside, while being a binding site for S...
Britta Mersch, Alexander Gepperth, Sándor S...
BMCBI
2008
135views more  BMCBI 2008»
14 years 10 months ago
Fregene: Simulation of realistic sequence-level data in populations and ascertained samples
Background: FREGENE simulates sequence-level data over large genomic regions in large populations. Because, unlike coalescent simulators, it works forwards through time, it allows...
Marc Chadeau-Hyam, Clive J. Hoggart, Paul F. O'Rei...
BMCBI
2008
166views more  BMCBI 2008»
14 years 10 months ago
Biclustering via optimal re-ordering of data matrices in systems biology: rigorous methods and comparative studies
Background: The analysis of large-scale data sets via clustering techniques is utilized in a number of applications. Biclustering in particular has emerged as an important problem...
Peter A. DiMaggio Jr., Scott R. McAllister, Christ...
BMCBI
2008
126views more  BMCBI 2008»
14 years 10 months ago
c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
Katerina Kechris, Hao Li
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