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AAAI
2007
13 years 8 months ago
Learning by Reading: A Prototype System, Performance Baseline and Lessons Learned
A traditional goal of Artificial Intelligence research has been a system that can read unrestricted natural language texts on a given topic, build a model of that topic and reason...
Ken Barker, Bhalchandra Agashe, Shaw Yi Chaw, Jame...
BMCBI
2010
99views more  BMCBI 2010»
13 years 6 months ago
Prediction of novel precursor miRNAs using a context-sensitive hidden Markov model (CSHMM)
Background: It has been apparent in the last few years that small non coding RNAs (ncRNA) play a very significant role in biological regulation. Among these microRNAs (miRNAs), 22...
Sumeet Agarwal, Candida Vaz, Alok Bhattacharya, As...
BMCBI
2008
128views more  BMCBI 2008»
13 years 6 months ago
Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate reg
Background: Gene expression measurements from breast cancer (BrCa) tumors are established clinical predictive tools to identify tumor subtypes, identify patients showing poor/good...
David D. Smith, Pål Sætrom, Ola R. Sn&...
BMCBI
2007
162views more  BMCBI 2007»
13 years 6 months ago
Genome-wide identification of specific oligonucleotides using artificial neural network and computational genomic analysis
Background: Genome-wide identification of specific oligonucleotides (oligos) is a computationallyintensive task and is a requirement for designing microarray probes, primers, and ...
Chun-Chi Liu, Chin-Chung Lin, Ker-Chau Li, Wen-Shy...
BMCBI
2006
123views more  BMCBI 2006»
13 years 6 months ago
Computational models with thermodynamic and composition features improve siRNA design
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
Svetlana A. Shabalina, Alexey N. Spiridonov, Aleks...