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BMCBI
2010
101views more  BMCBI 2010»
15 years 26 days ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...
CLUSTER
2007
IEEE
15 years 10 days ago
The computer as software component: A mechanism for developing and testing resource management software
— In this paper, we present an architecture that encapsulates system hardware inside a software component used for job execution and status monitoring. The development of this in...
Narayan Desai, Theron Voran, Ewing L. Lusk, Andrew...
CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
15 years 6 months ago
Latent Structure Models for the Analysis of Gene Expression Data
Cluster methods have been successfully applied in gene expression data analysis to address tumor classification. By grouping tissue samples into homogeneous subsets, more systema...
Dong Hua, Dechang Chen, Xiuzhen Cheng, Abdou Youss...
BMCBI
2010
115views more  BMCBI 2010»
15 years 26 days ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
RECOMB
2002
Springer
16 years 1 months ago
Discovering local structure in gene expression data: the order-preserving submatrix problem
This paper concerns the discovery of patterns in gene expression matrices, in which each element gives the expression level of a given gene in a given experiment. Most existing me...
Amir Ben-Dor, Benny Chor, Richard M. Karp, Zohar Y...