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» Tests for gene clustering
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CBMS
2008
IEEE
15 years 7 months ago
A New Path Length Measure Based on GO for Gene Similarity with Evaluation using SGD Pathways
We propose a new method for measuring the semantic similarity of genes based on path length between their annotation terms in the Gene Ontology. Our method applies an exponential ...
Anurag Nagar, Hisham Al-Mubaid
99
Voted
IJSI
2008
122views more  IJSI 2008»
15 years 24 days ago
Mining Gene Expression Data using Domain Knowledge
Biology is now an information-intensive science and various research areas, like molecular biology, evolutionary biology or environmental biology, heavily depend on the availabilit...
Nicolas Pasquier, Claude Pasquier, Laurent Brisson...
165
Voted
BMCBI
2007
265views more  BMCBI 2007»
15 years 27 days ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
86
Voted
BMCBI
2005
107views more  BMCBI 2005»
15 years 21 days ago
Identifying differential expression in multiple SAGE libraries: an overdispersed log-linear model approach
Background: In testing for differential gene expression involving multiple serial analysis of gene expression (SAGE) libraries, it is critical to account for both between and with...
Jun Lu, John K. Tomfohr, Thomas B. Kepler
99
Voted
BIOINFORMATICS
2010
109views more  BIOINFORMATICS 2010»
15 years 27 days ago
Phylogenetic networks do not need to be complex: using fewer reticulations to represent conflicting clusters
Phylogenetic trees are widely used to display estimates of how groups of species evolved. Each phylogenetic tree can be seen as a collection of clusters, subgroups of the species ...
Leo van Iersel, Steven Kelk, Regula Rupp, Daniel H...