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» Tests for gene clustering
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88
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BMCBI
2008
95views more  BMCBI 2008»
15 years 28 days ago
Gene set analyses for interpreting microarray experiments on prokaryotic organisms
Background: Despite the widespread usage of DNA microarrays, questions remain about how best to interpret the wealth of gene-by-gene transcriptional levels that they measure. Rece...
Nathan L. Tintle, Aaron A. Best, Matthew DeJongh, ...
89
Voted
BMCBI
2005
78views more  BMCBI 2005»
15 years 22 days ago
PREP-Mt: predictive RNA editor for plant mitochondrial genes
Background: In plants, RNA editing is a process that converts specific cytidines to uridines and uridines to cytidines in transcripts from virtually all mitochondrial protein-codi...
Jeffrey P. Mower
122
Voted
BMCBI
2008
126views more  BMCBI 2008»
15 years 28 days ago
c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
Katerina Kechris, Hao Li
BMCBI
2005
178views more  BMCBI 2005»
15 years 22 days ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
BMCBI
2011
14 years 4 months ago
Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in Bre
Background: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biologi...
Hiroko K. Solvang, Ole Christian Lingjærde, ...