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BMCBI
2004
100views more  BMCBI 2004»
15 years 14 days ago
Handling multiple testing while interpreting microarrays with the Gene Ontology Database
Background: The development of software tools that analyze microarray data in the context of genetic knowledgebases is being pursued by multiple research groups using different me...
Michael V. Osier, Hongyu Zhao, Kei-Hoi Cheung
ICCS
2005
Springer
15 years 6 months ago
Phylogenetic Networks, Trees, and Clusters
Phylogenetic networks model evolutionary histories in the presence of non-treelike events such as hybrid speciation and horizontal gene transfer. In spite of their widely acknowled...
Luay Nakhleh, Li-San Wang
111
Voted
BMCBI
2007
197views more  BMCBI 2007»
15 years 22 days ago
Boolean networks using the chi-square test for inferring large-scale gene regulatory networks
Background: Boolean network (BN) modeling is a commonly used method for constructing gene regulatory networks from time series microarray data. However, its major drawback is that...
Haseong Kim, Jae K. Lee, Taesung Park
108
Voted
BMCBI
2008
110views more  BMCBI 2008»
15 years 22 days ago
Testing for treatment effects on gene ontology
In studies that use DNA arrays to assess changes in gene expression, it is preferable to measure the significance of treatment effects on a group of genes from a pathway or functi...
Taewon Lee, Varsha G. Desai, Cruz Velasco, Robert ...
100
Voted
KDD
2001
ACM
142views Data Mining» more  KDD 2001»
16 years 1 months ago
TreeDT: gene mapping by tree disequilibrium test
We introduce and evaluate TreeDT, a novel gene mapping method which is based on discovering and assessing tree-like patterns in genetic marker data. Gene mapping aims at discoveri...
Petteri Sevon, Hannu Toivonen, Vesa Ollikainen