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» Tests for gene clustering
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78
Voted
KDD
2004
ACM
112views Data Mining» more  KDD 2004»
16 years 1 months ago
A rank sum test method for informative gene discovery
Finding informative genes from microarray data is an important research problem in bioinformatics research and applications. Most of the existing methods rank features according t...
Lin Deng, Jian Pei, Jinwen Ma, Dik Lun Lee
BMCBI
2007
140views more  BMCBI 2007»
15 years 22 days ago
From genes to functional classes in the study of biological systems
Background: With the popularisation of high-throughput techniques, the need for procedures that help in the biological interpretation of results has increased enormously. Recently...
Fátima Al-Shahrour, Leonardo Arbiza, Hern&a...
105
Voted
CSB
2003
IEEE
111views Bioinformatics» more  CSB 2003»
15 years 6 months ago
A Contradiction-Based Framework for Testing Gene Regulation Hypotheses
We have developed a mathematical framework for representing and testing hypotheses about gene, protein, and signaling molecule interactions. It takes a hierarchical, contradiction...
Steve Racunas, Nigam Shah, Nina V. Fedoroff
87
Voted
RECOMB
2008
Springer
16 years 28 days ago
Reconstructing the Evolutionary History of Complex Human Gene Clusters
Abstract. Clusters of genes that evolved from single progenitors via repeated segmental duplications present significant challenges to the generation of a truly complete human geno...
Adam C. Siepel, Eric D. Green, Giltae Song, Tom&aa...
BMCBI
2007
164views more  BMCBI 2007»
15 years 19 days ago
Comparison of probabilistic Boolean network and dynamic Bayesian network approaches for inferring gene regulatory networks
Background: The regulation of gene expression is achieved through gene regulatory networks (GRNs) in which collections of genes interact with one another and other substances in a...
Peng Li, Chaoyang Zhang, Edward J. Perkins, Ping G...