Expressed sequence tags (ESTs) have provided a first glimpse of the collection of transcribed sequences in a variety of organisms. However, a careful analysis of this sequence dat...
John Quackenbush, Feng Liang, Ingeborg Holt, Geo P...
Traditional clustering is a descriptive task that seeks to identify homogeneous groups of objects based on the values of their attributes. While domain knowledge is always the bes...
Background: In microarray gene expression profiling experiments, differentially expressed genes (DEGs) are detected from among tens of thousands of genes on an array using statist...
When building predictors of disease state based on gene expression data, gene selection is performed in order to achieve a good performance and to identify a relevant subset of ge...
Background: The unsupervised discovery of structures (i.e. clusterings) underlying data is a central issue in several branches of bioinformatics. Methods based on the concept of s...