Background: Biological processes are carried out by coordinated modules of interacting molecules. As clustering methods demonstrate that genes with similar expression display incr...
It is well-known that for high dimensional data clustering, standard algorithms such as EM and the K-means are often trapped in local minimum. Many initialization methods were pro...
Chris H. Q. Ding, Xiaofeng He, Hongyuan Zha, Horst...
The utilization of parallel processing in bioinformatics is a relatively new development, and wide spread use of parallel processing in this domain has been limited by the availab...
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
Background: To identify differentially expressed genes across experimental conditions in oligonucleotide microarray experiments, existing statistical methods commonly use a summar...
Leah Barrera, Chris Benner, Yong-Chuan Tao, Elizab...