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» Tests for gene clustering
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145
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BMCBI
2005
113views more  BMCBI 2005»
15 years 19 days ago
Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks
Background: Biological processes are carried out by coordinated modules of interacting molecules. As clustering methods demonstrate that genes with similar expression display incr...
Cecily J. Wolfe, Isaac S. Kohane, Atul J. Butte
114
Voted
ICDM
2002
IEEE
158views Data Mining» more  ICDM 2002»
15 years 5 months ago
Adaptive dimension reduction for clustering high dimensional data
It is well-known that for high dimensional data clustering, standard algorithms such as EM and the K-means are often trapped in local minimum. Many initialization methods were pro...
Chris H. Q. Ding, Xiaofeng He, Hongyuan Zha, Horst...
ITNG
2006
IEEE
15 years 6 months ago
Evaluating Parallel Computing Systems in Bioinformatics
The utilization of parallel processing in bioinformatics is a relatively new development, and wide spread use of parallel processing in this domain has been limited by the availab...
Erik S. Gough, Michael D. Kane
BMCBI
2008
159views more  BMCBI 2008»
15 years 25 days ago
Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via log
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
Dawei Liu, Debashis Ghosh, Xihong Lin
BMCBI
2004
113views more  BMCBI 2004»
15 years 18 days ago
Leveraging two-way probe-level block design for identifying differential gene expression with high-density oligonucleotide array
Background: To identify differentially expressed genes across experimental conditions in oligonucleotide microarray experiments, existing statistical methods commonly use a summar...
Leah Barrera, Chris Benner, Yong-Chuan Tao, Elizab...