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» Tests for gene clustering
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120
Voted
BMCBI
2004
165views more  BMCBI 2004»
15 years 18 days ago
Analysis of oligonucleotide array experiments with repeated measures using mixed models
Background: Two or more factor mixed factorial experiments are becoming increasingly common in microarray data analysis. In this case study, the two factors are presence (Patients...
Hao Li, Constance L. Wood, Thomas V. Getchell, Mar...
120
Voted
BMCBI
2008
160views more  BMCBI 2008»
15 years 25 days ago
A method for analyzing censored survival phenotype with gene expression data
Background: Survival time is an important clinical trait for many disease studies. Previous works have shown certain relationship between patients' gene expression profiles a...
Tongtong Wu, Wei Sun, Shinsheng Yuan, Chun-Houh Ch...
117
Voted
BMCBI
2008
145views more  BMCBI 2008»
15 years 25 days ago
Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis
Background: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, ...
Shameek Biswas, John D. Storey, Joshua M. Akey
111
Voted
BMCBI
2008
126views more  BMCBI 2008»
15 years 25 days ago
Methods for evaluating gene expression from Affymetrix microarray datasets
Background: Affymetrix high density oligonucleotide expression arrays are widely used across all fields of biological research for measuring genome-wide gene expression. An import...
Ning Jiang, Lindsey J. Leach, Xiaohua Hu, Elena Po...
107
Voted
BMCBI
2007
124views more  BMCBI 2007»
15 years 22 days ago
BranchClust: a phylogenetic algorithm for selecting gene families
Background: Automated methods for assembling families of orthologous genes include those based on sequence similarity scores and those based on phylogenetic approaches. The first ...
Maria S. Poptsova, J. Peter Gogarten