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IJBRA
2007
120views more  IJBRA 2007»
14 years 9 months ago
The myGrid ontology: bioinformatics service discovery
: In this paper we explore issues in the development of the my Grid ontology, which is an OWL ontology designed to support service discovery through service annotation. There are c...
Katy Wolstencroft, Pinar Alper, Duncan Hull, Chris...
BMCBI
2006
120views more  BMCBI 2006»
14 years 9 months ago
The Virtual Insect Brain protocol: creating and comparing standardized neuroanatomy
Background: In the fly Drosophila melanogaster, new genetic, physiological, molecular and behavioral techniques for the functional analysis of the brain are rapidly accumulating. ...
Arnim Jenett, Johannes E. Schindelin, Martin Heise...
BMCBI
2008
159views more  BMCBI 2008»
14 years 9 months ago
Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via log
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
Dawei Liu, Debashis Ghosh, Xihong Lin
BMCBI
2010
136views more  BMCBI 2010»
14 years 9 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2006
124views more  BMCBI 2006»
14 years 9 months ago
Detection of divergent genes in microbial aCGH experiments
Background: Array-based comparative genome hybridization (aCGH) is a tool for rapid comparison of genomes from different bacterial strains. The purpose of such analysis is to dete...
Lars Snipen, Dirk Repsilber, Ludvig Nyquist, &Arin...