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ARTMED
2007
347views more  ARTMED 2007»
14 years 9 months ago
A combined MRI and MRSI based multiclass system for brain tumour recognition using LS-SVMs with class probabilities and feature
Objective: This study investigates the use of automated pattern recognition methods on magnetic resonance data with the ultimate goal to assist clinicians in the diagnosis of brai...
Jan Luts, Arend Heerschap, Johan A. K. Suykens, Sa...
BMCBI
2010
106views more  BMCBI 2010»
14 years 9 months ago
A computational evaluation of over-representation of regulatory motifs in the promoter regions of differentially expressed genes
Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...
Guofeng Meng, Axel Mosig, Martin Vingron
BMCBI
2010
154views more  BMCBI 2010»
14 years 9 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
BMCBI
2010
139views more  BMCBI 2010»
14 years 9 months ago
PoGO: Prediction of Gene Ontology terms for fungal proteins
Background: Automated protein function prediction methods are the only practical approach for assigning functions to genes obtained from model organisms. Many of the previously re...
Jaehee Jung, Gangman Yi, Serenella A. Sukno, Micha...
BMCBI
2010
131views more  BMCBI 2010»
14 years 9 months ago
Prediction of epigenetically regulated genes in breast cancer cell lines
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...