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BMCBI
2010
105views more  BMCBI 2010»
14 years 9 months ago
Comparison of PGH2 binding site in prostaglandin synthases
Background: Prostaglandin H2 (PGH2) is a common precursor for the synthesis of five different Prostanoids via specific Prostanoid Synthases. The binding of this substrate with the...
Padmapriya Paragi-Vedanthi, Mukesh Doble
BMCBI
2010
151views more  BMCBI 2010»
14 years 9 months ago
Misty Mountain clustering: application to fast unsupervised flow cytometry gating
Background: There are many important clustering questions in computational biology for which no satisfactory method exists. Automated clustering algorithms, when applied to large,...
István P. Sugár, Stuart C. Sealfon
BMCBI
2010
156views more  BMCBI 2010»
14 years 9 months ago
Extended morphological processing: a practical method for automatic spot detection of biological markers from microscopic images
Background: A reliable extraction technique for resolving multiple spots in light or electron microscopic images is essential in investigations of the spatial distribution and dyn...
Yoshitaka Kimori, Norio Baba, Nobuhiro Morone
BMCBI
2010
139views more  BMCBI 2010»
14 years 9 months ago
TOPSAN: a collaborative annotation environment for structural genomics
Background: Many protein structures determined in high-throughput structural genomics centers, despite their significant novelty and importance, are available only as PDB depositi...
Dana Weekes, S. Sri Krishna, Constantina Bakolitsa...
BMCBI
2008
218views more  BMCBI 2008»
14 years 9 months ago
LOSITAN: A workbench to detect molecular adaptation based on a Fst-outlier method
Background: Testing for selection is becoming one of the most important steps in the analysis of multilocus population genetics data sets. Existing applications are difficult to u...
Tiago Antao, Ana Lopes, Ricardo J. Lopes, Albano B...