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» The Case for Grounding Databases
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BMCBI
2008
130views more  BMCBI 2008»
15 years 1 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
BMCBI
2010
117views more  BMCBI 2010»
15 years 1 months ago
MetAssimulo: Simulation of Realistic NMR Metabolic Profiles
Background: Probing the complex fusion of genetic and environmental interactions, metabolic profiling (or metabolomics/metabonomics), the study of small molecules involved in meta...
Harriet J. Muncey, Rebecca Jones, Maria De Iorio, ...
BMCBI
2010
136views more  BMCBI 2010»
15 years 1 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2010
187views more  BMCBI 2010»
15 years 1 months ago
PathEx: a novel multi factors based datasets selector web tool
Background: Microarray experiments have become very popular in life science research. However, if such experiments are only considered independently, the possibilities for analysi...
Eric Bareke, Michael Pierre, Anthoula Gaigneaux, B...
ARTMED
2006
86views more  ARTMED 2006»
15 years 1 months ago
Spatiotemporal reasoning about epidemiological data
Objective. In this article, we propose new methods to visualize and reason about spatiotemporal epidemiological data. Background. Efficient computerized reasoning about epidemics ...
Peter Z. Revesz, Shasha Wu