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BMCBI
2007
14 years 10 months ago
2007
Background: Several mathematical and statistical methods have been proposed in the last few years to analyze microarray data. Most of those methods involve complicated formulas, a...
BMCBI
2008
14 years 10 months ago
2008
Background: Molecular-docking-based virtual screening is an important tool in drug discovery that is used to significantly reduce the number of possible chemical compounds to be i...
BMCBI
2010
14 years 10 months ago
2010
Background: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostabilit...
BMCBI
2008
14 years 10 months ago
2008
Background: We present a methodology for high-throughput design of oligonucleotide fingerprints for microarray-based pathogen diagnostic assays. The oligonucleotide fingerprints, ...
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BMCBI
2007
14 years 10 months ago
2007
Background: Current methods for the automated generation of genome-scale metabolic networks focus on genome annotation and preliminary biochemical reaction network assembly, but d...