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BMCBI
2010
135views more  BMCBI 2010»
14 years 10 months ago
Quadratic variance models for adaptively preprocessing SELDI-TOF mass spectrometry data
Background: Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI) is a proteomics tool for biomarker discovery and other high throughput applicatio...
Vincent A. Emanuele II, Brian M. Gurbaxani
BMCBI
2008
104views more  BMCBI 2008»
14 years 10 months ago
Evolutionary Pareto-optimization of stably folding peptides
Background: As a rule, peptides are more flexible and unstructured than proteins with their substantial stabilizing hydrophobic cores. Nevertheless, a few stably folding peptides ...
Wolfram Gronwald, Tim Hohm, Daniel Hoffmann
BMCBI
2008
102views more  BMCBI 2008»
14 years 10 months ago
Fast splice site detection using information content and feature reduction
Background: Accurate identification of splice sites in DNA sequences plays a key role in the prediction of gene structure in eukaryotes. Already many computational methods have be...
A. K. M. A. Baten, Saman K. Halgamuge, Bill C. H. ...
CORR
2008
Springer
173views Education» more  CORR 2008»
14 years 9 months ago
Decomposition Principles and Online Learning in Cross-Layer Optimization for Delay-Sensitive Applications
In this paper, we propose a general cross-layer optimization framework in which we explicitly consider both the heterogeneous and dynamically changing characteristics of delay-sens...
Fangwen Fu, Mihaela van der Schaar
ECCC
2010
124views more  ECCC 2010»
14 years 9 months ago
Lower Bounds and Hardness Amplification for Learning Shallow Monotone Formulas
Much work has been done on learning various classes of "simple" monotone functions under the uniform distribution. In this paper we give the first unconditional lower bo...
Vitaly Feldman, Homin K. Lee, Rocco A. Servedio