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BMCBI
2010
170views more  BMCBI 2010»
14 years 12 months ago
Integrative analysis of gene expression and copy number alterations using canonical correlation analysis
Background: With the rapid development of new genetic measurement methods, several types of genetic alterations can be quantified in a high-throughput manner. While the initial fo...
Charlotte Soneson, Henrik Lilljebjörn, Thoas ...
BMCBI
2010
95views more  BMCBI 2010»
14 years 12 months ago
Spatio-structural granularity of biological material entities
Background: With the continuously increasing demands on knowledge- and data-management that databases have to meet, ontologies and the theories of granularity they use become more...
Lars Vogt
BMCBI
2008
112views more  BMCBI 2008»
14 years 12 months ago
GlycomeDB - integration of open-access carbohydrate structure databases
Background: Although carbohydrates are the third major class of biological macromolecules, after proteins and DNA, there is neither a comprehensive database for carbohydrate struc...
René Ranzinger, Stephan Herget, Thomas Wett...
BMCBI
2007
133views more  BMCBI 2007»
14 years 12 months ago
Semantic integration to identify overlapping functional modules in protein interaction networks
Background: The systematic analysis of protein-protein interactions can enable a better understanding of cellular organization, processes and functions. Functional modules can be ...
Young-Rae Cho, Woochang Hwang, Murali Ramanathan, ...
BMCBI
2010
122views more  BMCBI 2010»
14 years 12 months ago
Genome3D: A viewer-model framework for integrating and visualizing multi-scale epigenomic information within a three-dimensional
Background: New technologies are enabling the measurement of many types of genomic and epigenomic information at scales ranging from the atomic to nuclear. Much of this new data i...
Thomas M. Asbury, Matt Mitman, Jijun Tang, W. Jim ...