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» The Design and Analysis of Parallel Algorithms
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BMCBI
2008
116views more  BMCBI 2008»
14 years 10 months ago
Gene Ontology annotations: what they mean and where they come from
To address the challenges of information integration and retrieval, the computational genomics community increasingly has come to rely on the methodology of creating annotations o...
David P. Hill, Barry Smith, Monica S. McAndrews-Hi...
BMCBI
2006
153views more  BMCBI 2006»
14 years 10 months ago
Discovery of time-delayed gene regulatory networks based on temporal gene expression profiling
Background: It is one of the ultimate goals for modern biological research to fully elucidate the intricate interplays and the regulations of the molecular determinants that prope...
Xia Li, Shaoqi Rao, Wei Jiang, Chuanxing Li, Yun X...
BMCBI
2006
124views more  BMCBI 2006»
14 years 10 months ago
The development and validation of the Virtual Tissue Matrix, a software application that facilitates the review of tissue microa
Background: The Tissue Microarray (TMA) facilitates high-throughput analysis of hundreds of tissue specimens simultaneously. However, bottlenecks in the storage and manipulation o...
Catherine M. Conway, Deirdre O'Shea, Sallyann O'Br...
BMCBI
2007
154views more  BMCBI 2007»
14 years 10 months ago
Inferring biological networks with output kernel trees
Background: Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. Computational approaches to this problem ...
Pierre Geurts, Nizar Touleimat, Marie Dutreix, Flo...
BMCBI
2004
169views more  BMCBI 2004»
14 years 10 months ago
A power law global error model for the identification of differentially expressed genes in microarray data
Background: High-density oligonucleotide microarray technology enables the discovery of genes that are transcriptionally modulated in different biological samples due to physiolog...
Norman Pavelka, Mattia Pelizzola, Caterina Vizzard...