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155
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
144
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: Homology is a key concept in both evolutionary biology and genomics. Detection of homology is crucial in fields like the functional annotation of protein sequences and...
120
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: Genome assemblers have grown very large and complex in response to the need for algorithms to handle the challenges of large whole-genome sequencing projects. Many of ...
155
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: A goal of proteomics is to distinguish between states of a biological system by identifying protein expression differences. Liu et al. demonstrated a method to perform...
111
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: The prediction of conformational B-cell epitopes is one of the most important goals in immunoinformatics. The solution to this problem, even if approximate, would help...